大剂量MTX治疗儿童急性淋巴性白血病的观察与护理

Observation and nursing about high dose MTX(HDMTX) treatment of children acute lymphocytic leukemia(ALL)

目的 :研究大剂量甲氨蝶呤 (HDMTX)治疗儿童急性淋巴性白血病的疗效。方法 :对 2 9例次急性白血病患儿行HDMTX化疗 ,观察其毒副作用及实施有效的护理。结果 :阻止了肿瘤细胞的生长 ,缓解了病情 ,延长了患儿的生存期。结论 :加强对应用HDMTX患儿的治疗与护理 ,是减少MTX毒副作用反应的主要措施。

Objective:To research about treatment of children ALL with high dose MTX and its therapeutic outcome.Method:29 cases who receive HDMTX had been analyzed,its toxic side effects had been observed.Result:Tumor cells' growth had been inhibited,disease condition had been alleviated life sustaince had been enlongated.Conclusion:Treatment and nursing of children ALL should be strengthened to reduce MTX side reactions.