摘要
①目的 探讨获得性免疫缺陷综合征 (AIDS)病人外周血T淋巴细胞亚群和白细胞介素 6 (IL 6 )、白细胞介素 8(IL 8)水平的变化。②方法 采用碱性磷酸酶抗碱性磷酸酶 (APAAP)法和夹心酶联免疫吸附法检测 4例AIDS病人和 2 0例健康人T淋巴细胞亚群和IL 6、IL 8水平的变化。③结果 AIDS病人CD2、CD4、CD4 /CD8明显降低 ,而CD8和IL 6、IL 8则明显增高 ,与对照组比较差异均有极显著性 (t或t′=4 .37~ 17.19,P <0 .0 0 1)。④结论 T淋巴细胞亚群和IL 6、IL
Objective To explore the changes of T lymphocyte subsets and interleukin-6(IL-6) and IL-8 levels in AIDS patients. Methods The T lymphocyte subsets and IL-6 and IL-8 were measured in four AIDS patients and 20 normal controls by using alkaline phosphatase anti-alkaline phosphatase (APAAP) assay and sandwich enzyme linked immunosorbent assay (ELISA). Results CD2, CD4, and CD4/CD8 were lower, while CD8 and IL-6 and IL-8 were higher in AIDS patients than those in the controls (t or t′=4.37-17.19, P<0.001). Conclusion The detection of T lymphocyte subsets and IL-6 and IL-8 may be served to observe AIDS patients and monitor their responses to treatment.
出处
《齐鲁医学杂志》
2004年第2期153-153,155,共2页
Medical Journal of Qilu
关键词
AIDS
外周血
T淋巴细胞亚群
IL-6
IL-8
acquired immunodeficiency syndrome
T-lymphocyte subsets
interleukin-6
interleukin-8