卵巢浆液性肿瘤的电镜诊断

Electron Microscopic Diagnosis of Serous Tumor of the Ovary

对20例卵巢浆液性肿瘤进行了电镜观察,并与光镜观察对比。提出分支管道样腔、纤毛及顶浆分泌是浆液性肿瘤电镜诊断的主要指标。而核不规则形伴细桥和分叶核形成、核内胞浆包涵体及畸形核仁是确认细胞指征。纤毛杆的大量出现是肿瘤细胞分化成熟的表现,但纤毛杆缺如不一定是不成熟的征象。核糖体丰富及粗面內质网减少是癌细胞分化低下的表现?疚奶致哿私盒韵傧宋龅拿?认为改成浆液性纤维腺瘤更符合肿瘤命名原则。

Comparision with the light microscopic appearance, an electron microscopic observation was made on 12 caces of serous tumor of the ovary. It is suggested that branching cleft lumens, cilia and apocrine secretione are the main ultrastructural characteristics of serous tumor. Formation of tiny bridges with lobular nuclei, intranuclear cytoplasmic inclusions and bizarre nucleoli are the features of unquestionable cancer cells.The presence of numerous cilia is the feature of well-differentiated tumor cells, but the absence of cilia can not conclude that the tumor cells are immature. Abundant ribosome and lack of rough endoplasmic reticulum represent the low-differentiated tumor cells. The nomenclature of serous adenofibroma is also discussed. It is proposed that serous fibroadenoma is more accurate.