贲门癌术后肠外营养支持的临床观察

Clinical observation on the effect of parenteral nutrition in postoperative esophageal carcinoma patients

目的 :观察肠外营养 (PN)对贲门癌术后病人的疗效。 方法 :将 86例病人随机分为两组 ,即对照组 4 2例 ,用常规补液 ;PN组 4 4例 ,用PN治疗。 结果 :①PN可提高病人体力状况 ,减少体重下降幅度 ,降低白细胞数升高幅度 ,降低红细胞数、血红蛋白以及血清清蛋白下降幅度 ,与对照组比较差异显著 (P <0 .0 1 ) ;②PN组的病人吻合口瘘的发生率为 0 ,肺部感染发生率为 4 .5 5 % ,胸腔积液发生率为 4 .5 5 % ,切口愈合不良发生率为 0 ;对照组吻合口瘘的发生率为 7.1 4 % ,肺部感染发生率为 2 8.5 7% ,胸腔积液发生率为 1 9.0 5 % ,切口愈合不良发生率为 7.1 4 % ,两组比较差异显著 (P <0 .0 1 )。 结论 :贲门癌术后PN治疗可明显降低吻合口瘘及肺部感染等术后并发症 。

Objective: To observe the effect of parenteral nutrition(PN) on postoperative esophageal carcinoma patients. Methods: 86 patients were randomly divided into 2 groups,one as PN group and the other as contrast. Results: ①PN could improve body activity status,lessen the losses of body weight,red blood cells,hemoglobin and serum albumin, and decrease the raise of white blood cells.There was a significant difference between the two groups, P <0.01;②The rates of anastomatic,pulmonary infection,thoracicpleural effesion and incision healing badness were 0,4.55%,4.55% and 0 in PN group ,while they were 7.14%, 28.57%, 19.05% and 7.14% in control group. There was a significant difference between groups, P <0.01. Conclusions: PN can significantly lessen the occurrence of anastomatic fistula ,pulmonary infection and other postoperative complications in esophageal carcinoma patients.