4-羟基-2'-硝基二苯胺对水生生物急性毒性效应的研究

Acute Toxicity Effect of 4- Hydroxy- 2′ - Nitrodiphenylamine on Aquatic Organisms

采用静态生物急性试验的方法,研究了4-羟基-2'-硝基二苯胺对2个营养级别的水生生物(大型、斑马鱼和红鲫鱼)的急性毒性效应。结果表明,大型的幼接触不同浓度的毒性,活动会受到抑制,甚至死亡,48h的EC50为1.54mg·L-1;对斑马鱼和红鲫鱼也有明显的毒性作用,其96h的LC50分别为4.04和5.37mg·L-1。在2个营养级别的受试生物中,大型对该毒物的敏感性比斑马鱼和红鲫鱼强。根据化学物质对鱼类和类的毒性评价标准,4-羟基-2'-硝基二苯胺属于中等毒性的化合物。

The acute toxicity of 4- Hydroxy- 2′ - Nitrodiphenylamine to Daphnia magna, Zebro fish( Brachydanio rerio) and gold fish (Carassius Auratus) were studied, and safety assessment was also made in the aquatic ecosystem. 4- Hydroxy- 2′ - Nitrodiphenylamine remarkably restrained the mobilization of Daphnia magna, even causing them death, and EC50 value for D. magna at 48 h was 1.54 mg· L- 1. The chemical also had the toxicity effect on Zebra fish and gold fish, and LC50 values for them at 96 h were 4.04 and 5.37 mg· L- 1, respectively. Based on these E(L)C50 values, 4- Hydroxy- 2′ - Nitrodiphenylamine belonged to moderately toxic chemicals to aquatic organisms. Compared with Zebra fish and gold fish, Daphnia magna showed more sensitive to 4- Hydroxy- 2′ - Nitrodiphenylamine.