准分子激光原位角膜磨镶术后角膜厚度变化分析

Change of corneal thickness after laser in situ keratomileusis

目的 探讨如何更准确设定准分子激光原位角膜磨镶术 (LASIK)术中手术切削量 ,分析LASIK术后屈光度数回退的原因。方法 对 650例 (12 75只眼 )进行LASIK手术的患者术前、术中及术后 1周 ,1、3、6及 12个月追踪观察角膜厚度及屈光状态的变化。结果 通过术中角膜测厚发现准分子激光机显示的角膜切削深度与实际角膜切削深度平均相差 (3 2 15± 7 2 3 ) μm。角膜中央厚度变化在术后 6个月以后趋于稳定。屈光度数回退量与年龄、角膜床厚度呈负相关 ,与术前屈光度呈正相关。结论 LASIK术后角膜厚度和屈光状态的稳定需 6个月时间 ,年龄是影响LASIK术后屈光稳定性的主要因素之一 ,准确掌握术中的实际切削深度是提高手术安全性的保障。 (中华眼科杂志 ,2 0 0 4,40 :17 19)

Objective The corneal thickness was measured in and after in situ keratomileusis (LASIK) to investigate the accurate ablation depth on cornea during the operation and the possible mechanism of myopic after operation Methods From August 1999 to June 2000, 650 myopia patients were treated by LASIK The changes in cornea thickness were measured before, during and 1 week, 1, 3, 6 and 12 month after the surgery Results By the measurement of cornea thickness during the operation, the real cornea ablated thickness was (32 15±7 23) μm different from the expected value Central thickness of the cornea and the refraction could be stable in six months after the operation Conclusions The cornea thickness and the refraction would be stable in six months after the operation Age of the patients is the key factor that influences the stability of ocular refraction (Chin J Ophthalmol, 2004,40:17-19)