超声乳化白内障吸除术对血-房水屏障功能的影响

Disorders of the blood-aqueous barrier after phacoemulsification

目的 观察小切口超声乳化白内障吸除人工晶状体植入术及相关因素对血 房水屏障功能的影响。方法 使用激光蛋白细胞检测仪对 60例 (64只眼 )白内障患者超声乳化白内障吸除人工晶状体植入术前、后的房水蛋白浓度进行定量检测 ,记录并比较闪光值。术后随访时间为 3个月。结果 超声乳化白内障吸除人工晶状体植入术前 ,术后 1d、1周、1个月及 3个月术眼房水的平均闪光值分别为 (6 94± 0 3 4 )、(2 6 2 7± 1 3 7)、(13 96± 1 0 5)、(9 0 7± 0 43 )及 (7 16± 0 2 7)光粒子数 /ms ,其中术后 1d、1周及 1个月高于术前 ,且差异均有显著意义 (P <0 0 5) ;术后 3个月与术前比较 ,差异无显著意义 (P >0 0 5)。术后早期术眼房水蛋白浓度与患者年龄呈正相关 (r =0 40 0 ,P =0 0 0 1) ,与患者的性别和眼别均无相关。术中虹膜脱出者术后 1d和 1周血 房水屏障功能破坏严重。结论 超声乳化白内障吸除人工晶状体植入术在术后短期内影响术眼的血 房水屏障功能 ;激光蛋白细胞检测仪可动态评价超声乳化白内障吸除术对血 房水屏障功能的影响。 (中华眼科杂志 ,2 0 0 4,40 :2 6 2 9)

Objective To determine the st atus of blood-aqueous barrier after small incision phacoemulsification with implantation of foldable intraocular lens Methods The blood-aqueous barrier status in 64 eyes of 60 patients who underwent cataract surgery was examined using a laser flare cell meter The protein level of anterior chamber aqueous humor was evaluated by measurement of the flare value preoperatively and postoperatively Results The mean preoperative flare intensity was (6 94±0 34) photon counts/ms, which increased to (26 27±1 37), (13 96±1 05), (9 07±0 43) and (7 16±0 27) photon counts/ms on days 1, 7, 30 and 90 after the surgery, respectively Significantly statistical differences on flare values were found between preoperative data and those on days 1, 7 and 30 after surgery The blood-aqueous barrier was recovered on day 90 postoperatively The variables such as age, gender, eye (left/right) had no influence on the flare value Patients with iris prolapse had a higher flare value at day 1 and day 7 a fter the surgery Conclusions Blood-aqueous barrier after phacoemulsification with implantation of intraocular lens can be measured quantitatively by the laser flare cell meter The blood-aqueous barrier disorders can be recovered shortly after phacoemulsification (Chin J Ophthalmol,2004,40: 26-29)