大鼠睡眠剥夺方法的研究进展

Research progress of sleep deprivation methods in rats

目前睡眠的功能并不十分清楚,睡眠研究方法的不足很大程度上制约了睡眠研究及其理论的发展。睡眠剥夺是目前一种很有发展潜力的研究睡眠的手段,它对人们研究睡眠各期的功能有很强的启发性。在睡眠剥夺研究中,要想得到可靠的实验结果,需要有效专一地消除睡眠,因而,消除睡眠的睡眠剥夺方法在研究中有着很重要的意义。本文将几种常用的大鼠睡眠剥夺方法予以综述。

The function of sleep still remains uncertain. Methodological problems limit the research and the development of diverse theories. Sleep deprivation is a potentially powerful strategy for discovering the function of sleep.It is of heuristic value for the investigation of the functions of sleep states. The sleep deprivation method plays a key role in these investigations since valid conclusions can only be drawn in cases where the effects observed can be attributed exclusively to sleep suppression. In this paper, some commonly used sleep deprivation methods in rats were reviewed.