彩色多普勒超声对颈动脉粥样硬化病变的多因素分析

Analysing Multiple Factors of Color Doppler Ultrasound for Carotid Atherosclerosis

目的 应用彩色多普勒超声检查患者颈动脉病变 ,探讨年龄、高血压、冠心病、糖尿病、高脂血症及血浆同型半胱氨酸、超敏 C反应蛋白与颈动脉硬化程度的关系。方法 彩超检查 1 78例患者的颈动脉 ,测量管径、内中膜厚度、斑块大小、收缩期最大流速及计算管径狭窄度 ,观察内中膜厚度、斑块及管腔的狭窄、闭塞与年龄、高血脂、高血压、糖尿病、冠心病及血浆同型半胱氨酸、超敏 C反应蛋白的关系。结果 1 .随着年龄增高 ,患者颈动脉内中膜厚度、斑块、管腔狭窄及闭塞发生率均显著增高 ;2 .伴有高血压、糖尿病、冠心病、高血脂中 2种以上疾病者颈动脉斑块、管腔狭窄和闭塞发生率显著增高 ;3.同型半胱氨酸浓度的增高与颈动脉粥样硬化程度相关 ,颈动脉管腔狭窄和闭塞组患者血浆同型半胱氨酸显著高于其它两组 (P<0 .0 1 )。结论 年龄、高血压、糖尿病、冠心病。

Objective We examined patients carotid arteries using color Doppler ultrasound to analyse the relationship between carotid atherosclerosis and age,hypertension,coronary heart disease(CHD),diabetes,hyperlipidemia,homocysteine(Hcy)and hypersensitive CRP. Methods All carotid arteries of 178 cases were examined with color Doppler ultrasound and vascular diameters,intima media thicknes(IMT),plaques,blood stream velocities and the percentage of stenosis were measured. Results 1.With the patients age increasing,the occurrent rates of the carotid IMT.plaques,vascular stenoses and obliterations were higher and higher.2.The incidence of carotid plagues,stenoses and obliterations was higher when patients suffered from there diseases such as hypertension,CAD,diabetes and hyperlipidemia.3.The Hcy concentration of patients with carotid stenosis and obliterations was higher. Conclusions Age,hypertension,coronary disease,diabetes,hyperlipidemia and high Hcy concentration were correlated closely with carotid atherosclerosis.