前列腺钬激光剜除术与经尿道前列腺电切术的近期疗效比较

An evaluation of holmium laser enucleation of the proatate and transurethral resection of the prostate for the treatment of symptomatic BPH

目的 :比较前列腺钬激光剜除术 (HoLEP)和经尿道前列腺电切术 (TURP)近期疗效。方法 :将前列腺增生 (BPH)患者随机分为两组 ,分别行HoLEP和TURP ,监测、记录两组患者围手术期和术后 6个月复查指标 ,将所测指标进行统计学分析。结果 :术前两组一般情况比较差异无统计学意义 (P >0 .0 5 ) ;术后 6个月 ,两组国际前列腺症状评分、生活质量评分、最大尿流率均比术前得到明显改善 (P <0 .0 1) ;术中输血量、电切综合征发生率、术后平均膀胱冲洗时间、置管时间和住院时间 ,HoLEP组明显小于TURP组 (P <0 .0 1)。结论 :HoLEP治疗BPH具有与TURP相似的近期疗效 ;术中并发症发生率及患者术后恢复时间明显少于TURP ,是目前BPH激光疗法中最有望替代TURP的一种新方法。

Objective:To evaluate the clinical effect in the near future of holmium laser enucleation of the prostate(HoLEP) and transurethral resection of the prostate on benign prostatic hyperplasia(BPH).Method:80 patients who were diagnosised BPH actually were divided into two groups treated by either HoLEP or TURP randomizedly. The perioperative marker and theraputic results were recorded and analysied.Result:There was no significant difference of preoperative factors between the two groups. 6 months postoperatively, IPSS、QOLS and Q max were significantly improved. No signicicant difference in the improvement of subjective sympotoms and objective results has been noted with the different procedures. The incidence of blood transfusion and TURS occuring、the mean bladder irrigating time、catheration time、hospital stay time were significant shortor in HoLEP than in TURP.Conclusion:HoLEP is as effective as TURP for the treatment of symptomatic BPH. As HoLEP yields less adverse side effect and recovering time, it may be a substitute for TURP.