联合快速检测心肌损伤标记物在急性心肌梗死早期诊断中的应用分析

The study of united rapid measure of myocardial injury marker in early diagnosis of acute myocardial infarction

目的 评价联合快速检测心肌损伤标记物在急性心肌梗死 (AMI)中的早期诊断价值。方法 采用美国PMB公司的综合诊断试剂盒快速测定 4 7例AMI患者在不同时期的CK MB、Mb、TnI,同时用生化法测定CRP和CK MB ,进行统计学比较。结果 4种标记物早期 (≤ 6h)诊断灵敏性以血清Mb最高 ,CK MB最低。在AMI发病 3～ 7天 ,TnI阳性率非常显著高于其它 3种 (P <0 0 0 5 )。早期快速测试法测定CK MB的阳性率显著高于酶法 (P <0 0 5 ) ,而早期CRP阳性率与酶法CK MB相比亦有非常显著的差异 (P <0 0 1 )。

Objective To evaluate the value of united rapid measure of myocardial injury marker in early diagnosis of acute myocardial infarction(AMI) Methods PBM of USA reagent box was used to analytical the indexes in 47 cases of AMI at different time,Meantime,their CRP and CK MB were measured by biochemistry analytical way Results The diagnostic accuracy of Mb was the highest and that of CK MB was the lowest in early AMI(≤6h) Third to seventh day after attack of AMI,The positive rate of TnI was significantly higher than the others(P<0 005) In early AMI,the positive rate of CK MB(rapid measurement) was higher than the others(biochemistry analysis)(P<0 05) The positive rate of CRP was significantly higher than that of CK MB(biochemistry analysis) (P<0 01) Conclusions United rapid measure of myocardial injury marker is quite valuable in early diagnosis of AMI