摘要
目的 探讨应用免疫散射比浊法测定血浆D 二聚体 (D dimer,DD)与缺血性心脑血管疾病的关系。方法 采用近年应用于临床的免疫散射比浊法检测 6 3例缺血性心脑血管病患者的D 二聚体水平。结果 30例冠心病人及 33例脑梗死病人的血浆D 二聚体含量分别为 (36 8 77± 2 6 3 86 )ng/ml和 (6 4 4 6 4± 31 2 93)ng/ml,明显高于对照组 (93 5± 6 3 94ng/ml)。其中脑梗死病人D 二聚体含量增高更为显著 ,考虑与两种疾病的发病机制、病理生理有关。结论 用免疫散射比浊法定量分析检测 ,能客观地反映体内血栓形成及继发纤溶的程度 ,有待收集更多的临床数据 ,获取更有参考价值的资料 ,作为该类疾病的诊断、预后。
Objective To study the relationship between ischemic cardio cerebrovascular diseases and D dimer in plasma detected by immune scatter turbidimetry Method D dimer were detected by immune scatter surbidimetry in 63 patients with ischemic cardio cerebrovascular diseases Results D dimer of 30 coronary patients and 33 cerebral infarction patients was (368 77±263 86)ng/ml and (644 64±312 93)ng/ml respectively,which were significantly higher than the control group (93 5±63 94)ng/ml D dimer increased more significantly in cerebral infarction patients,which might be related to pathogenesis and pathology of these two deseases Conclusions Quantitative analysis of D dimer by immune scatter turbidimetry can objectively reflect the level of thrombosis and secondary fibrinolysis in vivo,which can be used in diagnosis and prediction of ischemic cardio cerebrovascular diseases and in monitoring of thrombolysis
出处
《广西医学》
CAS
2004年第5期658-660,共3页
Guangxi Medical Journal
