C反应蛋白测定在小儿肺炎中的应用

The Application If C Reaction Protein In Children with Pncumonia

目的 本研究的目的在了解C反应蛋白的(CRP)测定对于小儿肺炎的诊断价值。方法 连续选取20例白细胞总数不高的小儿肺炎患者,作回顾性研究对象。比较其治疗前和治疗后7-10d后疾病的痊愈或明显好转时CRP水平,并与体温、白细胞分类结果进行比较。结果 治疗后CRP水平(0.57±0.68ug/ml)显著低于治疗前水平(5.90±3.57ug/ml)P<0.001;治疗前CRP的阳性率为100％,显著高于嗜中性粒细胞比率>75％的阳性率(30％)和体温高于37.5℃的阳性率(30％),P<0.005。结论 CRP可以作为一种反映细菌感染的敏感指标,有助于不典型小儿肺炎的诊断和疗效观察。

Objective: To investigate the evaluation of CRP detection in diagnosis of pneumonia. Methods: 20 chilatren with Pneumonia were selected. The CRP levels were compared between before treatment and full re- covered after 7-10 days of treatment. Also the results of temperature and the classification of leucocytes were compared. Results The CRP level was significantly lower after treatment (0.57±0.68ug/ml)than before (3.90± 3.57ug/ml), P<0.001. The positive rate of CRP was higher than the rate of the group (30%)which the ratio was more than 75%and the group(30%) which temperature was higher than 37.5℃, P<0.005. Conclusion: CRP might be a sensitive index which can reflect bacteria inflaction, and help diangnosis and observe the offect of treat- ment in children atypical pneumonia.