上海市中老年戊型病毒性肝炎危险因素调查

Investigation on risk factors for hepatitis E of middle aged and elderly people in urban Shanghai

[目的 ] 了解上海市中老年戊型病毒性肝炎发病危险因素。 [方法 ] 病例对照调查 ,选择临床和血清学诊断为戊型病毒性肝炎的病人 14 4例作为调查对象 ,按 1∶2配比 2 88名对照者 ,采用单因素和多因素条件Logistic回归分析。 [结果 ] 单因素分析显示食用火锅、饭前便后不洗手、到个体摊点和饮食店就餐、食用河鲜类食物为戊型病毒性肝炎发病的主要危险因素 ,经多因素条件Logistic回归模型分析 ,OR值分别为 4.718、3 .0 5 8、2 .117和 2 .14 7。 [结论 ] 上海市中老年戊型病毒性肝炎发病仍以食用火锅、饭前便后不洗手、到个体摊点和饮食店就餐。

Objective] To explore the risk factors for hepatitis E (HE)of middle aged and elderly people in urban Shanghai. [Methods] Cases diagnosed as HE by clinic and serology from Dec 1st 2000 to Nov 29th 2001 were chosen for study altogether 144 and matched with 288 controls. Both single factor and multiple factors conditional Logistic regression method were adopted in analysis. [Results] The risk factors were eating chafing dish, not washing hands before meals or after defecation, eating in stalls or trattorias and eating freshwater fish. Their OR values were 4.718, 3.058, 2.117 and 2.147 respectively. [Conclusion] Eating chafing dish, not washing hands before meals or after defecation, eating in stalls or trattorias and eating freshwater fish were still the most important risk factors for hepatitis E in urban shanghai.