细菌性阴道病与不良妊娠结局的关系

The Relationship Between Bacterial Vaginosis and Dys-cyosis

目的探讨细菌性阴道病(bacterialvaginaosis,BV)与胎膜早破、早产、宫内感染、宫内发育迟缓(IUGR)、低出生体重儿等不良妊娠的关系。方法依据临床表现和阴道分泌物革兰氏染色涂片镜检,对60例胎膜早破、60例早产、60例宫内感染、60例宫内发育迟缓(IUGR)、60例低出生体重儿的孕妇(研究组)和同期的健康孕妇60例(对照组)的阴道分泌物进行BV的检测。同时对50例合并BV产妇的新生儿和50例非BV产妇的新生儿血清胆红素进行检测。结果胎膜早破、早产、宫内感染、宫内发育迟缓(IUGR)、低出生体重儿合并BV的检出率分别为28.3%(17/60)、20.0%(12/60)、26.7%(16/60)、21.7%(13/60)、28.3%(17/60),分别与对照组8.3%(5/60)比较差异有显著性(P<0.05)。同时合并BV孕妇的新生儿血清胆红素明显升高,出现新生儿高胆红素血症。结论细菌性阴道病(BV)与不良妊娠结局有关,有必要对妊娠的孕妇进行产前BV的常规检测,以便及早治疗。

Objective To investigate the relationship between bacterial vaginosis and dys cyosis, such as premature rapture of membranes, premature birth, intrauterine infection, IUGR and giving birth to low body weight babies. Methods Bacterial vaginosis (BV) was diagnosed by clinical symptoms and viginal discharge microscope examination in 60 patients with premature rapture of membranes, 60 patients with premature birth, 60 patients with intrauterine infection, 60 patients with IUGR and 60 patients with giving birth to low body weight babies. Viginal discharge microscope examination also performed in 60 normal controls. At the same time, serum bilirubin levels were examined in 50 meonates from no BV mothers and meonates from BV mothers. Results Incidence of BV was 28.3% in patients with premature rapture of membranes, 26.7% in patients with intrauterine infection, 21.7% in IUGR, 28.3% patients with giving birth to low body weight babies and only 8.3% in normal controls(P< 0.05 respectively ). The levels of serum bilirubin was increased apparently in BV gravida. Conclusion BV is related to dys cyesis. Routine examination was necessary to pregnant women.