左氟沙星与司帕沙星口服治疗非淋菌性尿道(宫颈)炎的成本-效果分析

Cost-effectiveness Analysis of Levofloxacin and Sparfloxacin in the Treatment of Nongonococcus Urethritis(Cervicitis) Patients

目的 :评价口服左氟沙星与司帕沙星治疗非淋菌性尿道 (宫颈 )炎 (NGU )的成本 -效果。方法 :采用循证医学的方法收集临床资料 ,应用药物经济学的成本 -效果分析法对口服左氟沙星与司帕沙星治疗NGU进行评价。结果 :左氟沙星与司帕沙星治疗NGU的治愈率分别为71 16 % (62 00 % ,80 32 % )、81 69 % (78 71 % ,85 21 % ) ,C/E分别为2 29、2 71 ,ΔC/ΔE为5 57。结论 :虽然司帕沙星疗效优于左氟沙星 ,但成本 -效果分析表明 ,左氟沙星更具成本 -效果优势。

OBJECTIVE:To evaluate the cost-effectiveness of levofloxacin and sparfloxacin in the treatment of nonˉgonococcus urethritis(cervicitis)patients.METHODS:The clinical data of levofloxacin and sparfloxacin in the treatment of nongonococcus urethritis were collected with evidence-based medicine method and were evaluated with pharmacoeconomic cost-effectiveness analysis.RESULTS:The cure rates of two drugs were71.16%(62.00%,80.32%),81.69%(78.71%,85.21%)and cost-effectiveness ratios were2.29and2.71respectively.TheΔC/ΔE was5.57.CONCLUSION:The cost-efˉfectiveness ratio of levofloxacin was lower than that of sparfloxacin although the cure rate of sparfloxacin for nongonococcus urethritis was better.