在骨髓长期培养中基质细胞间的相互关系

Relationship between Various Stromal Cells in Long Term Bone Marrow Culture

本实验观察,在骨髓长期培养中各种基质细胞间的相互关系和特殊的连接结构。免疫电镜观察表明,上皮样基质细胞具有分泌纤维结合蛋白(Fn)的功能,后者在细胞与基质及细胞间的连接中起介导作用。

In the present studies, the relationship and special junctions between various stromal cells in long term bone marrow culture were reported. The possible significance of these signs vis-a-vis the hemopoietic microenvironment were discussed.Fibronectin and thrombospondin were detected on the substratum and surface of the stromal cells using immunogold techniques. These adhesion proteins on the stromal cells might be important in cell-cell and cell-stroma connection.