急性心肌梗死溶栓后24小时内T波倒置的临床观察

Clinical Study of T wave Inversion after Thrombolysis Within 24 Hours in Patients with Acute Myocardial Infarction

目的 :探讨急性心肌梗死溶栓后 2 4小时内T波倒置与冠脉再通的关系及临床意义。方法 :将 5 6例接受溶栓治疗的患者分为A组 (倒置组 )和B组 (未倒置组 ) ,根据临床间接血管再通标准观察两组冠脉再通情况及临床意义。结果 :两组冠脉再通率分别为 72 .4 %和 33.3% (P <0 .0 1) ;住院期间左室射血分数分别为 (5 7.5± 11.6 ) %和 (4 6 .2± 13.2 ) % (P <0 .0 1) ;住院期间冠脉事件发生率分别为 13.7%和 37.0 % (P <0 .0 5 )。结论 :急性心肌梗死溶栓后 2 4小时内T波倒置可作为冠脉再通的临床间接指标 ,同时提示更好的临床预后。

Objective: To study the relationship between T wave inversion and coronary reperfusion within 24 hours after thrombolysis in patients with acute myocardial infarction (AMI). Methods: 56 AMI patients who received thrombolytic therapy were assign in the group A (with T wave inversion) and group B (without T wave inversion). The coronary reperfusion ratio, level of LVEF and in-hospital coronary event was compared between the two groups. Results: The coronary reperfusion ratio in group A and B were 72.4% and 33.3% respectively (P<0.01), the level of LVEF were (57.5±11.61)% and (46.2±13.21)% respectively (P<0.01), in-hospital coronary event were 13.7% and 37.0% (P<0.05). There was a significant difference in all these indices between the two groups. Conclusion: T wave inversion that occurs within 24 hours after thrombolysis could be regard as an indirect index of coronary reperfusion in the patients with AMI. Also, it may indicate better clinical outcome.