期刊文献+

锶离子对α-磷酸钙骨水门汀改性的研究 被引量:3

PROPERTY IMPROVEMENT BY STRONTIUM IONS ON α-TRICALCIUM PHOSPHATE CEMENT
下载PDF
导出
摘要 目的 :探讨锶离子对α 磷酸钙骨水门汀进行改性后的性能变化。方法 :在α 磷酸钙骨水门汀粉末中加入碳酸锶对该系统进行改性 ,使用x线衍射、原子能谱进行Sr2 + 的变化分析 ,考察固化体的凝固时间、压缩强度、溶解率以及锶离子在固化过程中的变化。结果 :骨水门汀的凝固时间满足临床操作的要求 ,在 37℃、PBS液中浸泡 5天后最高压缩强度达 2 8 7MPa ,溶解率增大 ,提高了表面生物反应性。结论 :用锶离子对α 磷酸钙骨水门汀系统改性后可改善其体外降解性能 。 Objective:To investigate the property change of α tricalcium phosphate cement modified by strontium ions.Methods:In this study α tricalcium phosphate cement was modified by strontium ions.The setting time,compressive strength,rate of dissolution and the change of strontium ions in solidifying process were investigated.Results:The setting time of cement could meet the expectation of clinical operation.The compressive strength of cement was enhanced up to 28 7 MPa after immerging in the PBS at 37 ℃ for 5 days and the rate of dissolution and biological reactivity increased.Conclusion:α tricalcium phosphate cement modified by strontium ions can improve the dissolubility in vitro and compressive strength of cement.
出处 《北京口腔医学》 CAS 2004年第2期73-76,共4页 Beijing Journal of Stomatology
关键词 锶离子 α-磷酸钙 骨水门汀 压缩强度 溶解率 Strontium ions Property improvement calcium phosphate cement compressive strength Rate of dissolution
  • 相关文献

参考文献9

  • 1廖大鹏,周正炎,顾云峰,陈德敏.锶磷灰石修复下颌骨缺损的实验研究[J].上海口腔医学,2000,9(2):73-75. 被引量:20
  • 2宁丽,菊池正纪,青木秀希,薛淼.生物陶瓷骨种植及其与骨组织结合机理的探讨[J].口腔材料器械杂志,1996,5(1):21-24. 被引量:4
  • 3Oreffo RO, Driessens FC, Planell JA et al. Growth and differentiation of human bone marrow osteopro-genitors on novel calcium phosphate cements. Biomaterials. 1998; 19(20) :1845
  • 4Cook SD, Thomas KA, Kay JF. Experimental coating defects in hydroxylapatite-coated implants. Clin Orthop. 1991;(265): 280
  • 5Neumann RD, Ruby AL, Ling GV et al. UI trastructure and mineral composition of urinary calculi from horses. Am J Vet Res. 1994;55(10): 1357
  • 6Grynpas MD, Hamilton E, Cheung R et al. Strontium increases vertebral bone volume in rats at a low dose that does not induce detectable mineralization defect. Bone. 1996:18(3):253
  • 7Okayama S, Akao M, Nakamura S et al. The mechanical properties and solubility of strontium - substituted hydroxyapatite. Biomed Mater Eng. 1991; 1 (1): 11
  • 8Christoffersen J, Christoffersen MR, Kolthoff N et al. Effects of strontium ions on growth and dissolution of hydroxyapatite and on bone mineral detection. Bone. 1997; 20 (1):47
  • 9Okayama S, Akac M, Nakarnura S et al. The mechanicul properties and solubility of strontium-substituted hydroxyapatite. Biomed Mater Eng, 1991; 1 (1): 11

二级参考文献2

共引文献22

同被引文献39

  • 1唐佩福,王继芳,卢世璧,王岩,卢世琳,贺大为,郝立波,毛克,黄晋香,孙明学,汪爱媛,赵彬.抗稀散性碳酸化羟基磷灰石骨水泥的研究[J].北京生物医学工程,2005,24(3):161-165. 被引量:4
  • 2赵晓云,郭大刚,憨勇,徐可为.含锶磷酸钙骨水泥的制备及性能研究[J].无机材料学报,2005,20(5):1167-1173. 被引量:10
  • 3郭永锦,陈治清,曾泉.含锶磷酸钙骨水门汀的理化性能和水化产物[J].福建医科大学学报,2007,41(1):39-42. 被引量:1
  • 4While E, Sots EC. Biomaterial aspects of Interpore-200 porous hydroxyapatite [J]. Dental Clinics of North America, 1986, 30 (1) :49-67.
  • 5Xu HHK, Eichmiller FC, Giuseppetti AA. Reinforcement of a self-setting calcium phosphate cement with different fibers [J]. J Biomed Mater Res, 1999, 52(3):107-114.
  • 6Chang BS, Lee CK, Hong KS, et al. Osteoconduction at porous hydroxyapatite with various pore configurations [J]. Biomaterials, 2000, 21(12) :1291-1298.
  • 7Takagi S, Chow LC. Formation of macropores in calcium phosphate cement implants [J]. J Mater Sci: Mater Med, 2001, 12 (2) :135-139.
  • 8Wang HB, Jong K, Moursi A, et al. Ca/P ratio effects on the degradation of hydroxyapatite in vitro [J]. J Biomed Mater Res, 2003, 67(2):599-608.
  • 9Tang RK, Henneman ZA, Nancollas GH. Constant composition kinetics study of carbonated apatite dissolution [J]. J Cry Grow, 2003, 249(3) :614-624.
  • 10Wrong CT, Chen QZ, Lu WW, et al. Ultrastructural study of mineralization of a strontium-containing hydroxyapatite (SrHA) cement in vivo [J]. Biomed Mater Res, 2004, 70(3):428- 435.

引证文献3

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部