相转移催化合成N-烃基咔唑

Synthesis of N-Alkylcarbazole by Phase transfer Catalysis Method

研究了在聚乙二醇— 4 0 0 (PEG— 4 0 0 )、聚乙二醇— 6 0 0 (PEG— 6 0 0 )、聚乙二醇— 80 0 (PEG— 80 0 )、四丁基溴化铵(TBAB)、四丁基氯化铵 (TBAC)、苄基三乙基氯化铵 (TEBA)、十六烷基三甲基溴化铵 (HTAB)、十六烷基三甲基氯化铵(HTAC)为相转移催化剂催化作用下 ,咔唑与溴代烃反应合成了 8个N -烃基咔唑 ,并通过元素分析 ,IR ,1 HNMR和MS对N

Eight N-alkylcarbazole were synthesized from carbazole and bromohydrocarbons with polyethylene glycol—400、polyethylene glycol—600、polyethyleneglycol—800、tetrabutylammonium bromide、tetrabutylammonium chloride、benzyltriethylammonium chloride、hexadecy trimethylammonium bromide and hexadecy trimethylammonium chloride as the phase transfer catalysts respectively.Their structures were determined by elementary analysis,IR, 1HNMR,and MS spectra.