摘要
用硫酸庆大霉素和硫酸黏杆菌素混合制剂菌威克对试验性鸡大肠杆菌病进行了预防与治疗试验。硫酸庆大霉素和硫酸黏杆菌素对鸡大肠埃希氏菌的最小抑菌浓度分别为 7.5× 10 - 4mg/L和 5 .9× 10 - 5mg/L ,最小杀菌浓度分别为 1.5× 10 - 3mg/L和 1.2× 10 - 4mg/L。在成本相近的情况下 ,以杀菌效果最佳比例配制的菌威克制剂的疗效要高于单独使用任何一种药物。预防与治疗试验结果表明 ,大剂量与中剂量菌威克对鸡大肠杆菌病的预防与治疗效果高于低剂量菌威克与单独应用硫酸庆大霉素和硫酸黏杆菌素的效果 (P <0 .0 5 )。
The prevention and treatment tests against experimental colibacillosis in chickens were (carried) out using Junweike preparation which was made from gentamycin sulfate and colisin sulfate. The results showed that MICs of gentamycin sulfate and colisin sulfate against Escherichia coli strain were (7.5×10^(-4) (mg/L)) and 5.9×10^(-5) mg/L respectively, and MBCs of the two drugs against E.coli were (1.5×10^(-3)) mg/L and 1.2×10^(-4) mg/L respectively. It was found that the bactericide efficacy of the best ratio of (gentamycin) to colisin was better than that of gentamycin sulfate or colisin sulfate alone. The (prevention) and treatment tests showed that the efficacy of prevention and treatment of the high and middle doses of Junweike preparation were significantly higher than those of the preparation at low dose, gentamycin (sulfate) and colisin sulfate (P<0.05).
出处
《中国兽医科技》
CSCD
北大核心
2004年第6期56-58,共3页
Chinese Journal of Veterinary Science and Technology
