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新疆地区猪戊型肝炎血清流行病学调查 被引量:36

Epidemic Investigation of Swine Hepatitis E Virus Infection in Xinjiang Region
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摘要 The purpose of the present study was to determine the prevalence of swine Hepatitis E virus (HEV) infection in Xinjiang. 813 swine serum samples collected from 1 to 12 months of age at 9 swine farms in Xinjiang region were tested by ELISA for the presence of IgG antibodies against HEV. The recombinant protein pUS166 containing region 452-617aa of the ORF2 of HEV US strain was used as coating antigen. The result showed that anti –HEV IgG were detected in 265 of 405 pigs (65.43%) in one group and 238 of 408 pigs (58.33%) in another group , and that the seropositivity rate was not related to geographic district and breeds, but differed remarkably by age, being 40% among the 1- to 3-month-old piglets, but 77.33% among ones over 3-month-old. It suggested that swine HEV was widespread in different geographic regions of XinJiang. The purpose of the present study was to determine the prevalence of swine Hepatitis E virus (HEV) infection in Xinjiang. 813 swine serum samples collected from 1 to 12 months of age at 9 swine farms in Xinjiang region were tested by ELISA for the presence of IgG antibodies against HEV. The recombinant protein pUS166 containing region 452-617aa of the ORF2 of HEV US strain was used as coating antigen. The result showed that anti –HEV IgG were detected in 265 of 405 pigs (65.43%) in one group and 238 of 408 pigs (58.33%) in another group , and that the seropositivity rate was not related to geographic district and breeds, but differed remarkably by age, being 40% among the 1- to 3-month-old piglets, but 77.33% among ones over 3-month-old. It suggested that swine HEV was widespread in different geographic regions of XinJiang.
出处 《中国病毒学》 CSCD 2004年第3期285-287,共3页 Virologica Sinica
关键词 戊型肝炎病毒 猪血清 酶联免疫吸附试验 Hepatitis E virus Swine serum ELISA s
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参考文献3

  • 1Masaharu Takhashi,Tsutomu Nishizawa,Haruko Miyajima,et al.Swine hepatitis E virus strains in Janpan from phylogenetic clusters comparable with those of Japanese isolate of human hepatitis E virus[J].J Gen Virol,2003,84:851-862.
  • 2Meng X J,Purcell R H,Harbur P G,et al.Anovel virus in swine is closely related to the hepatitis E virus [J].Proc Natl Ac Sci USA,1997,94(18):9860-9865.
  • 3Wu J C,Chen C M,Chiang T Y,et al.Spread of hepatitis Evirus among different-aged pigs:two-year survey in Taiwan[J].J Med Virol,2002,66(4):488-492.

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