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乳铁蛋白肽的研究进展 被引量：19

Progress of study on lactoferricin
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摘要 　乳铁蛋白肽(Lactoferricin,Lfcin)是动物乳汁中的乳铁蛋白(Lactoferrin,LF)在动物消化道中经酸性胃蛋白酶降解后产生的含25～28个氨基酸的小肽,它具有杀菌、抗病毒、抗真菌等多种独特的生物学活性,对动物具有保护功能。本文概述了乳铁蛋白肽的结构、生物学功能、国内外研究动态及其应用前景。 Lactoferricin is a kind of small peptide which derives from lactoferrin when it is digested by pepsin in gastrointestinal tract. It contains 25～28 amino acid residues and has various sheltered biological functions to (human) and animal, such as bacterial killing, fungal resisting and viral inhibition and so on. This review discusses structure, bio-functions and progress of study on lactoferricin at home and abroad.
作者 黄海青 汪以真
机构地区 浙江大学饲料研究所
出处 《中国兽药杂志》 2004年第6期15-18,共4页 Chinese Journal of Veterinary Drug
关键词 乳铁蛋白肽 Lfcin结构 生物学功能 环状结构 保护功能 Lfcin progresss
分类号 S852 [农业科学—基础兽医学]
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参考文献15

  • 1Wu M,Maier E,Benz R,et al.Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli[J].Biochemistry,1999,38: 7235-7242.
  • 2Yamauchi K,Tomita M,Gichl TJ,et al.Antibacterial activity of lactoferrin and a pepsin-derived lactoferrin peptide fragment[J].Infect Immun,1993,61(2):716-728.
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同被引文献258

引证文献19

二级引证文献57

中国兽药杂志
2004年 第6期

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