艾叶挥发油β-环糊精包合物的制备

Including Technique of β-cyclodextrin towards the Volatile Oils of Folic artemisiae

为了探索艾叶挥发油 β-环糊精包合的最佳生产工艺 ,提高挥发油在制剂中的稳定性。本文采用正交实验法 ,通过测定油利用率、包合物收得率及含油率考察包合工艺。结果表明 :最佳生产工艺条件 :A3 B2 C3 (β -环糊精和艾叶挥发油的比例为 8∶1,油和乙醇的比例为 1∶1.5 ,包合温度为 6 0℃ ,时间为 2h)。

In the paper,the authors explored the optimal including process of volatile oil withβ-cyclodextrin to increase the stability of volatile oil in medicine. Orthogonal experiment was used comparing with the utilization ratio of oil, receiving of inclusion and oil content,the results indicated that the optimal including process was A3B2C3 (the proportion of β-cyclodextrin and oil is 8∶1,the proportion of oil and alcohol is 1∶1.5,the temperature of including is 60℃,the time of including is 2 hours.)