28例Ⅰ期卵巢恶性生殖细胞肿瘤的治疗分析

TREATMENT OF PATIENT WITH STAGE I MALIGNANT GERM CELL TUMOR OF THE OVARY: A REPORT OF 28 CASES

28例1期卵巢恶性生殖细胞肿瘤中,13例作瘤侧附件切除,15例作双侧附件全子宫切除,术后均加化疗。全组五年生存率85.71％,瘤侧附件切除为84.6％,双侧附件全子宫切除为86.67％(P>0.05)。作瘤侧附件切除的13例中,2例复发死亡,2例复发后再次切除子宫卵巢加化疗后健在,9例成功地保留了正常卵巢及子宫。3例已结婚,并均正常分娩1次。本文着重讨论保留生育功能问题。

Twenty eight cases with stage I malignant germ cell tumor of ovarywere treated in our hospital during January 1964 to December 1985. Unilateral salpingo-oophorectomy was performed in 13 cases. Bi-lateral salpingo-oophorectomy and hysterectomywas performed in 15 cases. Post operative chemotherapy was given in all patients.. Theduration of follow-up was .more than. 5 years, Twenty four of 28 cases (85.71% ) were alive well. Survival rate of unilateral salpingo-oophorectomy was 84.6%, survival rate of bilateral salpingo-oophoretomy and hystorectomy was 86 .67% (P> 0.05). Four of 13 cases who recived unilateral salpingo-oophorectomy had recurrence of the disease. Preservation of normal ovary and uterus was successful in 9 cases. Among them 3 cases had pregnancy and delivery. The problem of preservation of fertility was discussed in this paper.