摘要
采用显微荧光光度术和细胞分裂完全阻断法研究了骆驼蓬总碱对小鼠腹水型肝癌细胞动力学的影响。结果表明:骆驼蓬总碱(60mg/kg)对对数生长期细胞有显著生长抑制作用,抑制率53.4％;阻滞细胞从G2期向M期转化,细胞积聚于G2期。这为临床联合用药提供了依据。
The effects of the total alkaloid of harmala . (TAH) on hepatoma cell cytokinetics in mice were studied by means of microfluorometric method and stathmokinetic method , These results showed that TAH inhibits the transition of cells from G2 to M phase and cells are accumulated in G2 phase. This provided basis for the combination chemotherapy of TAH with other conventional chemotherapeutic agents
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1993年第6期489-491,共3页
Chinese Journal of Cancer
关键词
骆驼蓬总碱
细胞动力学
肿瘤
Alkaloid of harmala Cytokinetics Microfluorometry Stathmokinesis
