血管吻合用中空支架壁双层结构的研究

Twolayer structure of the hollow stent wall for bloodvessel anastomosis

目的:研制一种血管吻合用支架,使其外表面光滑柔软,内层又具有快速溶解的特性。方法:选用高纯度低分子量明胶和色谱纯分子量为20000的聚乙二醇为原料制备血管吻合用中空支架,使前者构成支架壁的表层,后者构成支架壁的内层,并观察在类吻合环境下支架表面结构的改变。结论:双层血管吻合用支架在吻合环境中具有光滑柔软的外表面,能够快速溶解,适于血管吻合。

A stent for bloodvessel anastomosis, with a slippery, soft out layer and a rapidly soluble inner layer, is developed in this paper. The out layer is made up of the gelatin with a high purity and a low molecular weight, and the inner one of polyglycol with a molecular weight of 20000. The structure changes of the stent surface are studied with anastomosis environment simulated. The result proves that the stent can be applied to bloodvessel anastomosis