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FOXC2基因与肥胖 被引量:2

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摘要 FOXC2基因是新近发现的与脂肪细胞代谢有关的转录因子,属翼状螺旋/叉头转录因子家族。转基因小鼠高表达FOXC2可避免发生肥胖、高甘油三酯血症和饮食诱导的胰岛素抵抗。在人体中,FOXC2可调节脂肪细胞代谢,改善胰岛素敏感性。FOXC2基因多态性存在种族及性别差异。FOXC2可能是肥胖和胰岛素抵抗的候选基因。
出处 《国外医学(内分泌学分册)》 2004年第3期160-162,共3页 Foreign Medical Sciences(Section of Endocrinology)
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