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米非司酮避孕作用的机理研究 被引量:8

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摘要 米非司酮(mifepristoneRU486),一种孕激素拮抗剂,是临床应用极为广泛的抗早孕药物,还具有潜在的避孕作用,其避孕效果已在临床得到验证,无论每日低剂量还是排卵后立即给予大剂量米非司酮,抑或用于紧急避孕均可取得良好效果。其作用机理主要包括:抑制子宫内膜的生长和分泌期改变、阻止孕卵着床、抑制卵泡的发育和排卵。就米非司酮的避孕作用机理进行综述。
出处 《国外医学(计划生育分册)》 2004年第2期70-73,共4页
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参考文献23

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同被引文献23

  • 1程利南.米非司酮用于常规避孕[J].实用妇产科杂志,2006,22(2):65-66. 被引量:20
  • 2周青松.黄体初期短程应用米非司酮治疗子宫内膜异位症37例疗效分析[J].中国实用妇科与产科杂志,2006,22(9):702-703. 被引量:15
  • 3胡静,吴尚纯,孙红珠,苗莲,王晨,丛捷,董敬,张薇,肖碧莲.单次服用25mg米非司酮用于紧急避孕的临床效果观察[J].中国计划生育学杂志,1996,4(6):326-328. 被引量:44
  • 4全国宫内节育器临床研究组.不同时期放置宫内节育器的临床效果和副反应观察[J].中华妇产科杂志,1987,22:350-350.
  • 5Audrey Brown, Linan Cheng, Suiqing Lin, et al. Daliy low-dose mifepristone has contraceptive potential by suppressing ovulation and menstruation:a double-blind randomized control trial of 2 and 5rag per day of 120 days. J Clin Endocrinol Metab,2002,87(1): 63-70.
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