原发性肺癌患者睡眠质量的调查

Survey of quality of sleep in patients with primary lung cancer

目的:进行原发性肺癌患者睡眠质量的调查,研究其规律性,寻求干预方法。方法:84例原发性肺癌患者(肺癌组)按相同年龄、性别、职业、文化程度和婚姻状态与正常人(对照组)1∶1配对比较,治疗前1周肺癌组分别接受了睡眠质量调查、疼痛主诉分级和精神卫生症状自评量表(symptomchecklist-90,SCL-90)评估,对照组测试在体检期间进行。结果:在睡眠质量比较中,肺癌组的入睡(1.13±0.43)、睡眠维持(0.39±0.04)、睡眠自评(0.80±0.15)、睡眠总时间(0.93±0.20)等因子评分和睡眠质量总分(4.92±0.87)均明显高于对照组(t=2.095～2.941,P<0.01～0.05)。肺癌患者按疼痛主诉分级法分级后,疼痛程度重组(2～3级,39例)的入睡、睡眠维持、睡眠自评、午休时间、睡眠总时间、梦记忆情况等因子评分和睡眠质量总分均明显高于疼痛程度轻组(0～1级,45例)(t=2.178～2.674,P<0.01～0.05)。肺癌患者按SCL-90总分分组后,高SCL总分组(≥140,35例)的入睡、睡眠维持、睡眠自评、睡眠总时间和睡眠质量总分均明显高于SCL总分正常组(<140,49例)(t=2.078～2.296,P均<0.05)。结论:原发性肺癌患者有明显的睡眠质量下降,后者与疼痛程度和精神心理状态密切相关。

AIM:To survey the quality of sleep in patients with primary lung cancer,and to study its regularity so as to discuss the possible intervention. METHODS:Eighty four patients with primary lung cancer(lung cancer group) were matched with 84 normal subjects(control group) at the ratio of 1∶1 in the same age,gender,profession,educational level and marital status.One week before treatment,the patients in the lung cancer group received the inventory of sleep quality,the evaluation of verbal rating scale(VRS) and symptom checklist 90(SCL 90),but the subjects in the control group were only received the measurement of sleep quality survey during treatment. RESULTS:In comparison of sleep quality survey between the two groups,the scores of factors of falling asleep(1.13±0.43),maintaining sleep(0.39±0.04),sleep self assessment(0.80±0.15) and total time of sleep(0.93±0.20) as well as the total score of sleep quality(4.92±0.87) in the lung cancer group were significantly higher than those in the control group(t=2.095-2.941,P< 0.01-0.05).After the patients in the lung cancer group were divided into severe pain group(VRS 2-3 grade,39 cases) and mild pain group(VRS 0-1 grade,45 cases) in terms of different pain levels according to the VRS,the values of falling asleep,maintaining sleep,sleeping self assessment,time of midday rest,general time of sleep and memory of dream as well as the total score of sleep quality in the severe group were significantly higher than those in the mild group(t=2.178-2.674,P< 0.01-0.05). After the patients in the lung cancer group were divided into high SCL 90 group(≥140,35 cases) and normal SCL 90 group(< 140,49 cases) according to the SCL 90 scales,the values of falling asleep,maintaining sleep,sleeping self assessment,general time of sleep and the total score of sleep quality in the high SCL 90 group were significantly higher than those in the normal SCL 90 group(t=2.078-2.296,P< 0.05). CONCLUSION:The quality of sleep in patients with primary lung cancer decreases obviously,which is intimately related to the degrees of pain and mental state.