心肌缺血后再灌注钙超载的机理被引量：3

Mechanisms of Calcium Overload in Ischemic Reperfused Myocardium

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摘要目前心肌缺血后再灌注钙超载机理仍未彻底阐明 ,本文从胞质膜 (SL)裂隙、电压依赖性Ca2 + 通道、Na+ Ca2 + 交换、肌浆网 (SR)Ca2 + ATP酶、线粒体 (Mit)、氧自由基、磷脂酶、蛋白激酶C、钙调蛋白等方面进行了综述。 The precise mechanism of calcium overload in ischemic reperfused myocardium is still not clearly understood.This review describes the effects of sarcolemmal gap,voltage-depedent Ca 2+channels,Na+/Ca 2+exchange,Ca 2+-ATPase of the sarcoplasmic reticulum,mitochondria,oxygen free radicals,phospholipase,protein kinase C and calmodulin.

作者钱培刚陈竞纬顾仁樾

机构地区上海中医药大学研修部上海中医药大学附属龙华医院

出处《心血管病学进展》 CAS 2004年第3期229-232,共4页 Advances in Cardiovascular Diseases

关键词心肌缺血再灌注钙超载线粒体氧自由基磷脂酶 myocardium,ischemia reperfusion injury,calcium overload

分类号 R541.4 [医药卫生—心血管疾病]

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参考文献38

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