C_2对称的类卟啉手性双噁唑啉的合成及其应用

Syntheses of Novel Chiral Porphyrin-Resembling C_2-symmetric Bis(oxazoline) and Its Application

合成了 6个具有C2 对称性的类卟啉手性双唑啉配体 ,将这些化合物与RuCl3 配位 ,NaIO4作氧化剂 ,应用于反式1,2 二苯基乙烯的不对称环氧化反应 ,获得了较高的产率 ( 4 6.0 % ) ,但ee值 ( 6.3 % )

Novel chiral porphyrin-resembling C-2-symmetric bis(oxazoline) ligands 1a similar to 1f were synthesized, and their RuCl3 complexes using NaIO4 as an oxidatant were applied in the epoxidation of trans-stilbene with good yield (46.0%), but poor ee value (6.3%).