精浆α-1,4糖苷酶测定及其在无精子症鉴别诊断中的意义

MEASUREMENT OF α-1,4-GLUCOSIDASE IN HUMAN SEMINAL PLASMA. AND ITS SIGNIFICANCE IN DIFFERENTIAL DIAGNOSIS OF AZOOSPERMIA

本文测定了40例具有正常生育力男子和57例无精子症患者精浆α-1,4糖苷酶活力,其活力水平分别为42.4±18.4miu/ml和27.6±18.9miu/ml。无精子症组显著低于正常组(P<0.01)。在无精子症组中16例梗阻性无精子症患者该酶活力水平为10.7±8.2miu/ml,而余41例诊断不明的无精子症患者酶活力水平为34.025=21.3mlu/ml。梗阻性无精子症组显著低于以上各组(均为P<0.01)。提示精浆α-1,4糖苷酶测定对梗阻性无精子症有肯定的诊断意义。

Activity of α-1, 4-glucosidase in seminal plasma from 40 fertile men and 57 patients with azoospermia were measured, the mean values are 42.2±18.4 miu/ml and 27.6±18.9 miu/ml respectively. There is a significant difference between the 2 groups (P<0.01). The activity of this enzyme in 16 patients with excretory azoospermia is 10.7±8.2 miu/ml, but 34.02±21.3 miu/ml in other 41 patients with azoospermia. It shows a marked reduction excretory azoospermia group in comparsion with other groups (P<0.01). It suggests that there is a diagnostic value for excretory azoospermia to measure the activity of α-1,4-glucosidase in seminal plasma.