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Bayesian Decision Theory and its Applications in Early Phase Clinical Trails

Bayesian Decision Theory and its Applications in Early Phase Clinical Trails
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摘要 Bayes'theorem is named after the Reverend Thomas Bayes who proposed the idea in the 18th century[1].It has been adapted by scientists for many different applications.One of the applications is clinical trials,where decisions are guided by clinical expertise as well as by data,especially in early phases.This paper reviews Bayes' theorem,decision theory and their applications in clinical trials. Bayes' theorem is named after the Reverend Thomas Bayes who proposed the idea in the 18th century ~ . It has been adapted by scientists for many different applications. One of the applications is clinical trials, where decisions are guided by clinical expertise as well as by data, especially in early phases. This paper reviews Bayes' theorem, decision theory and their applications in clinical trials.
作者 ZHOUYing-hui
出处 《苏州大学学报(工科版)》 CAS 2004年第2期23-26,共4页 Journal of Soochow University Engineering Science Edition (Bimonthly)
关键词 贝叶斯定理 决策论 临床试验 早期症状 诊断 Bayes' theorem decision theory clincal trials early phases.
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  • 1Bayes T.An essay towards solving a problem in the doctrine of chances.Philosophical Transactions of the Royal Society of London 1763,53:370-418.
  • 2Zhou Y,Whitehead J.Practical implementation of Bayesian dose-escalation procedures.Drug Information Journal.2003,37:45-59.
  • 3Whitehead J,Brunier H.Bayesian decision procedures for dose determining experiments.Stat.Med.1995,14:885-893.
  • 4Whitehead J,Williamson D.An evaluation of Bayesian decision procedures for dose-finding studies.J.Biopharmaceutical Medicine.1998,8:445-467.
  • 5Patterson S,Francis S,Ireson M,et al.D A novel Bayesian decision procedure for early-phase dose finding studies.J.Biopharmaceutical Statistics.1999,9:583-597.
  • 6Whitehead J,Zhou Y,Patterson S,et al Easy-to-implement Bayesian methods for dose-escalation studies in healthy volunteers.Biostatistics.2001,2:47-61.
  • 7Stallard N.Sample size determination for phase II clinical trials based on Bayesian decision theory.Biometrics.1998,54:279-294.
  • 8Stallard N,Thall PF,Whitehead J.Decision theoretic designs for phase II clinical trials with multiple outcomes.Biometrics.1999,55:971-977.
  • 9Pocock S J.Clinical trials:a practical approach.London:Wiley.1983.
  • 10Lee P M.Bayesian statistics:an introduction.Oxford:OUP.1989.

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