妊娠期肝内胆汁淤积症患者脐血流检测与围产儿预后

Fetal Umbilical Artery Blood Flow Examination and Fetal Well Being in Patients w ith Intrahepatic Cholestasis of Pregnancy

目的 :探讨妊娠期肝内胆汁淤积症 (ICP)患者胎儿脐动脉血流阻抗特点及围产儿结局的影响。方法 :用胎儿脐血流检测仪检测 130例 ICP患者和 6 0例正常孕妇胎儿脐动脉血流阻力指标 S/ D和 PI。结果 :ICP组的 S/ D和 PI平均值均高于对照组 (P<0 .0 0 1) ;ICP组的 S/ D和 PI结果异常的围产儿预后不良发生率明显高于结果正常者 (P<0 .0 5和 P<0 .0 0 5 )。结论 :ICP患者应常规进行胎儿脐动脉血流阻力检测 ,以便及时处理 ,改善 ICP患者围产儿预后。

Objective:To study the resistant parameters of fetal umbi lical aretry blood flow in patients with intrahepatic cholestasis of pregnancy (ICP). Methods :130 patients with ICP and 60 healthy women in their late pregnancy were studied .S/D and PI, the blood flow resistance of fetal umbilical artery were determine d. Results:The average value of the S/D and PI of the ICP group were both high er t han the value of the control group (P<0.001). The incid ence of poor perinatal o utcomes of the ICP group which had abnormal results, was evidently higher than t h e normal ones(P<0.05 and P<0.0 05). Conclusion: Patients with ICP should receive determination of fetal umbilical artery blood flow resistance routinely in orde r to deal with in time to improve fetal well being.