严重急性呼吸道综合征170例患者肝功能变化的临床分析

Clinical analysis on liver function of 170 patients with severe acute respiratory syndrome

目的探讨严重急性呼吸道综合征(SARS)患者在病程中肝功能的变化规律,以进一步认识SARS的临床特征。方法以在太原市5大医院住院治疗的170例SARS患者为研究对象,定期检查肝功能。结果多数患者转氨酶[包括丙氨酸转氨酶(ALT)和天冬氨酸转氨酶(AST)]在疾病的第9天62.5%患者ALT升高,所有患者血清总蛋白始终正常,而40%～72%的患者血清白蛋白降低。结论SARS患者病程中可出现肝功能的异常,防治中应予以注意。

Objective To understand liver function of SARS better and accumulate more experience in preventing and treating this disease.Methods The liver function of 170 cases with SARS was analyzed; the cases were admitted in 5 hospitals in Taiyuan during Mar^May,2003.Results About 33%～63% of cases with high ALT(above 40 U/L),19%～40% of cases with high AST(above 40 U/L),and 40%～72% of cases with low albumin.But serum total protein remained normal during the whole clinic course.Conclusion SARS case may develop abnormal liver function.