人参茎叶总皂甙对孕鼠及其胎鼠的致突变作用

MUTATION EFFECTS OF GINSENOSIDES FROM STEMS AND LEAVES ON THE MATERNAL AND FOETAL MICE

本文应用妊娠小鼠及其胎鼠肝脏细胞的姐妹染色单体互换及微核试验,探讨人参茎叶总皂甙是否诱发母、胎遗传物质的损伤。实验结果证实,人参茎叶总皂甙对孕鼠及其胎儿组织无诱变作用。

The mutation effects of ginsenosides from stems and leaves of Panax ginseng (GNS) on the maternal bone marrow and the foetal liver were studied with sister chro-matid exchange (SCE) and the micronucleus test. The results showed that GNS did not bring about any genetic damage.