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子宫内膜异位症与肿瘤转移基因关系的研究进展 被引量:16

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摘要 子宫内膜异位症是常见的妇科良性疾病,但却具有恶性肿瘤的侵袭和转移特征,因此,探讨子宫内膜异位症的发病和转移的机制不仅对子宫内膜异位症的临床诊断、治疗有着重要的意义,同时对阐明恶性肿瘤的转移机制也有一定的作用。子宫内膜异位症的发生有一定的遗传基础;目前已知MMPs和TIMPs在子宫内膜重构中起重要的作用,MMPs和TIMPs的异常表达可以促进子宫内膜异位的发生,但其调节和相互作用的机制仍不明确;nm23基因在子宫内膜异位症的发生和发展过程中的作用也不清楚。
作者 孙青 孔丽娜
出处 《国外医学(遗传学分册)》 2004年第3期184-187,共4页 Foreign Medical Sciences(Section of Genetics )
基金 安徽省教育厅自然科学基金(2003kj313)
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