同种异体带瓣主动脉行主动脉根部置换的临床效果

Clinical results of homologuous aortic with valve replacement of aortic root

目的 :探讨应用低温保存的同种异体带瓣主动脉行主动脉根部重建手术的临床效果。方法 :85例主动脉瓣膜病变患者行同种主动脉根部置换手术 ,术后随访观察临床结果。结果 :随访 39± 13(1.5～ 91)个月。早期手术死亡率 1% (1/ 85 ) ,远期手术死亡率 6 % (5 / 85 ) ;与术前比较心功能明显改善 (P<0 .0 5 ) ;术后随访心内膜炎发生率占2 % (2 / 85 ) ;生存者中瓣膜无或有轻度返流 84 % (6 6 / 79) ,中度返流 16 % (13/ 79)。结论 :同种异体带瓣主动脉根部重建手术效果可靠 ,且并发症少。

AIM: To evaluate the clinical results of homologuous aortic with valve replacement for aortic root diseases. METHODS: There were 85 patients underwent aortic root replacement with a cryopreserved homologuous aortic with valve. The incidence rate of complications were carried out. RESULTS: The mean follow-up time was 39±13 (range 1.5~91) months. Early and late mortality postoperatively was 1 %(1/85) and 6%(5/85), respectively. The morbidity endocarditis was only 2%(2/85).The heart function have markly improvement postoperatively.Homograft valve function showed no or trivial and moderate aortic regurgitation in survival patients was 84%(66/79) and 16%(13/79),respectively. CONCLUSION: The aortic root replacement with cryopreserved homologuous aortic with valve has acceptable hospital mortality and excellent mid-term results compare with other artificial valve.