癔球症患者上食管括约肌运动功能研究

Study on Upper Esophageal Sphincter Motility in Patients with Globus Sensation

目的:探讨上食管括约肌(UES)运动功能与癔球症的关系。方法:采用Polygraf HR^(TM)食管测压系统对22例癔球症患者进行UES运动功能测定,25例健康志愿者作为对照组。结果:癔球症组UES长度、静息压、松弛压及松弛率[(3.6±0.6)cm、(43.4±8.0)mm Hg(1mm Hg=0.133 kPa)、(0.3±0.8)mm Hg,100％]与对照组[(3.5±0.7)cm、(41.8±8.5)mm Hg、(0.45±0.9)mm Hg、100％]比较差异均无统计学意义(P>0.05)。咽与UES的协调性均较好。结论:癔球症患者的UES运动功能是正常的,UES功能状况可能与癔球症的发生无关。

To investigate the relationship between upper esophageal sphincter (UES) motility and globus sensation. Methods: UES motility was measured with Polygraf HR^(TM) Esophagus Manometry System in 22 patients with globus sensation (patients' group) and 25 healthy volunteers(volunteers' group). Results: UES length, UES resting pressure, UES relax pressure and UES relax rate of patients' group[(3.6±0.6) cm, (43.4±8.0)mm Hg, (0.3±0.8)mm Hg and 100%,respectively] were not significantly different with those of control group[(3.5±0.7)cm, (41.8±8.5)mm Hg, (0.4+0.9) mm Hg and 100%, respectively] ( P>0.05, respectively). The coordinated motility of pharynx and UES was good. Conclusion: UES motility is normal in patients with globus sensation. There is no relation between UES function status and globus sensation.