禽多杀性巴氏杆菌强毒株与弱毒株制备的蜂胶灭活疫苗免疫原性的比较试验

Comparative tests on the immunity of inactivated propolis vaccines of virulent and attenuated poultry Pasteurella multocida

用禽多杀性巴氏杆菌强毒株(C48 1)与弱毒株(G190E40和B26 T1200)制备的蜂胶灭活疫苗的免疫原性对比试验结果表明,强毒株C48 1制备的禽霍乱蜂胶灭活疫苗的免疫效果显著高于弱毒株G190E40和B26 T1200,近期保护率相差20%～40%,3个月后相差40%～80%。强毒株C48 1的免疫原性显著高于弱毒株G190E40和B26 T1200,说明禽多杀性巴氏杆菌荚膜上的毒力蛋白可能具有免疫原性。

This paper compared the immunity of inactivated vaccine of virulent poultry Pasteurella multocida( ( C48-1) )with those of the attenuated ones( G190E40 and B26-T1200). The results showed that the immunity of the inactivatied propolis vaccine of C48-1 is higher than those of G190E40 and B26-T1200 by 20%～40% (recently) and 40%～80% three months later, which may suggest that the toxic protein in pod membrane of poultry (Pasteurella) multocida has immunity.