美洲大蠊(Periplaneta americana L.)抗菌肽杀菌作用初步观察

Observations on bactericidal action of antibacterial peptide from Periplaneta americana L.

报道了美洲大蠊(PeriplanetaamericanaL.)抗菌肽对大肠杆菌(EscherichiacoliK88)的作用过程.电镜观察表明,美洲大蠊抗菌肽首先使细菌的外层及细胞质膜损伤,形成开口,导致内容物外泄而死亡,最后菌体崩解成碎片.

Electron microscope was used to study the mechanism of bactericidal effect of antibacterial peptide. The primary targets were the outer layer and membrane, they were seriously injured and inner matterial leaked out. Bacterial cells became empty vesicles and tattered.