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A novel Rad gene polymorphism combined with obesity increases risk for type 2 diabetes mellitus

A novel Rad gene polymorphism combined with obesity increases risk for type 2 diabetes mellitus
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出处 《Chinese Medical Journal》 SCIE CAS CSCD 2004年第5期770-771,共2页 中华医学杂志(英文版)
关键词 Rad gene·obesity · polymorphism·type 2 diabetes mellitus Rad gene·obesity · polymorphism·type 2 diabetes mellitus
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  • 2S. Nishi,M. Stoffel,K. Xiang,T. B. Shows,G. I. Bell,J. Takeda.Human pancreatic Beta-cell glucokinase: cDNA sequence and localization of the polymorphic gene to chromosome 7, band p 13[J]. Diabetologia . 1992 (8)
  • 3K. C. Chiu,M. A. Province,G. K. Dowse,P. Z. Zimmet,G. Wagner,S. Serjeantson,M. A. Permutt.A genetic marker at the glucokinase gene locus for Type 2 (non-insulin-dependent) diabetes mellitus in Mauritian Creoles[J]. Diabetologia . 1992 (7)
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  • 6Chiu KC,Province MA,Permutt MA.Glucokinase gene is genetic marker for NIDDM in American Blacks. Diabetes . 1992
  • 7Stoffel M,Froguel PH,Takeda J,et al.Human glucokinase gene:isolation,characterization,and identification of two missense mutations linked to early-onset non-insulin-dependent(type 2) diabetes mellitus. Proceedings of the National Academy of Sciences of the United States of America . 1992
  • 8Noda K,Matsutani A,Tanizawa Y,et al.Polymorphic microsatellite repeat markers at the glucokinase gene locus are positively associated with NIDDM in Japanese. Diabetes . 1993
  • 9Permutt MA,Chiu KC,Tanizawa Y.Glucokinase and NIDDM:A candidate gene that paid off. Diabetes . 1992
  • 10Hattersley AT,Turner RC,Permutt MA,et al.Linkage of type 2 diabetes to glucokinase gene. The Lancet . 1992

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