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Overexpression of amyloid precursor protein inhibits neurite outgrowth and disrupts cytoskeleton in N2a cells 被引量:3

Overexpression of amyloid precursor protein inhibits neurite outgrowth and disrupts cytoskeleton in N2a cells
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出处 《Chinese Medical Journal》 SCIE CAS CSCD 2004年第5期775-778,共4页 中华医学杂志(英文版)
基金 ThisworkwassupportedinpartbygrantsfromtheNationalNaturalScienceFoundationofChina (No .3 992 5 0 12,3 9970 80 8,and30170221),theScienceandTechnologyCommitteeofChina (No .G19990 54007),andtheNationalEducationalCommitteeofChina (No.2 0 0 1 171)
关键词 Alzheimer's disease ·β-amyloid precursor protein · neurofilament · neurite Alzheimer's disease ·β-amyloid precursor protein · neurofilament · neurite
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参考文献10

  • 1KangJ,LemaireH,UnterbeckA etal.TheprecursorofAlzheimer’sdiseaseamyloidA4proteinresemblesacell surfacereceptor[].Nature.1987
  • 2MattsonMP.Cellularactionsofβ amyloidprecursorproteinanditssolubleandfibrillogenicderivatives[].Physiological Reviews.1997
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  • 7FrreiraA,CaceresA,KosikK.Intraneuronalcompartmentoftheamyloidprecursorprotein[].The Journal of Neuroscience.1993
  • 8MattsonMP.Secretedformsofβ amyloidprecursorproteinmodulatedendriteoutgrowthandcalciumresponsetoglutamateinculturedembryonichippocampalneurons[].JNeurobiol.1994
  • 9MaruyamaK,KumagaeY,SsitoY etal.ThetoxiceffectofAlzheimer’samyloidproteinprecursoroverexpressionintheneuroblastomacelllineNB 1onneuriteoutgrowth[].Journal of Gerontology.1994
  • 10WangJZ,LiXT,TongYC etal.HyperphosphorylationandaccumulationofneurofilamentproteinsinAlzheimer’sdiseasebrainandinokadaicacid treatedSY5Ycells[].FEBS Letters.2001

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