胸腺继发萎缩的病理学研究

Pathological Study of the Secondary Atrophy of Thymus

通过对212例围产儿胸腺组织的病理检查和动物实验表明:1.本组胸腺正常者53例占25.0%,重度萎缩49例占23.1%,轻度萎缩110例占51.9%,2.胸腺的重度萎缩率与有无感染、病程长短、营养状态、是否采用类固醇药物等因素有重要关系。3.根据动物实验、免疫组化和电镜检查结果提示:重度继发萎缩的胸腺仍有功能且并非完全不可恢复。

Based on the pathological examinations of 212 perinatal thymus autopsies and animal experiments, the results of present study were as follows: 1. The results of thymus examinations were composed (23.1%); mild atrophy 110 cases (51.9%). 2. There were important correlations between the incidence of severe atrophy of the thymus and infection, course of the disease, nutritional condition, use of steriod. 3. According to the animal experiments, immunohistochemistry and electron microscopic examinations, the results showed that even in severe atrophy cases the thymus functions are sometimes exhibited and their structures may be recovered.