摘要
为了解决接触式点样法制备生物芯片过程中 ,点样样点大小如何估算的问题 ,对样品分配机理进行了理论分析 ,讨论了点样针针尖大小、点样速度及溶液表面张力系数等因素对点样样点大小的影响 ,并进行了试验验证 .最后根据试验数据总结出了点样样点的估算公式 。
In order to solve the problem of estimating the sample spot diameters in fabricating biochip, the liquid dispensing principles were analyzed. The affections to the sample spot diameters by the factors, such as the tip diameters, printing velocities and liquid characters, were tested and discussed. According to the experimental data, the estimation formula of sample spot diameters was put forward.
出处
《北京航空航天大学学报》
EI
CAS
CSCD
北大核心
2004年第4期308-311,共4页
Journal of Beijing University of Aeronautics and Astronautics
基金
国家 8 63基金资助项目 ( 2 0 0 1AA42 2 190 )