急性有机磷中毒患者心肌酶谱的改变及其意义

Myocardium zymogram's changes and their significance of acute organophosphate poisoning patiens

目的 :探讨急性有机磷中毒 (AOPP)患者心肌酶谱的改变及内在机制。方法 :对 78例AOPP患者和正常人 2ml静脉血 ,测定心肌酶谱。结果 :轻中度中毒组患者心肌酶谱测值显著高于正常对照组 (P≤ 0 .0 1) ;重度中毒心肌酶谱测值显著高于轻中度中毒组 (P≤ 0 .0 1) ;呼吸肌麻痹组心肌酶谱显著高于重度中毒组 (P≤ 0 .0 1)。结论 :AOPP越重 ,心肌酶谱的水平升高越显著 ,反映心肌损伤越严重。

Objective: In order to study Myocardium zymogram's changes and its clinical significance of acute organophosphate poisoning patients. Methods: To measure myocardium zymogram from 2ml venous blood in 78 AOPP patients and 40 normal peoples. Results: The level of myocardium zymogram in the light-moderate intoxicated grounp is remarkably higher than that in normal contrast group(P≤0.01) ;The level of myocardium zymogram in the serious intoxicated group is remarkably higher than that in the light-moderate intoxicated group(P≤0.01); The level of myocardium zymogram in the pneumamyo paralysis group is remarkably higher than that in the serious intoxicated group(P≤0.01). Conclusion: The more seriously the AOPP patients are got , the higher the level of myocardium zymogram increased,the more severely the cardiac issue is damaged.