OGTT在FBG正常时诊断IGT和DM的作用

Diagnostic effect of OGTT on DM and IGT under normal FBG

目的 :探讨空腹血糖 (FBG)正常时糖尿病 (DM)和糖耐量减低 (IGT)的发生规律。方法 :研究对象为排除了已确诊的糖尿病、急性疾病、外伤手术、急、慢性肝病、妊娠妇女及其它患有影响糖代谢疾病患者的健康体检者。根据其OGTT试验服糖后 2h血糖 ( 2hPG)结果 ,将研究对象分为三组 :DM组、IGT组、正常组。结果 :在FBG正常 ( 4 .0～ 6 .0mmol/L)时 ,有 91例DM ,占DM组 ( 2 92例 )的 31.2 % ,占FBG正常例数 ( 30 71例 )的 2 .96 % ;有 4 6 6例IGT ,占IGT组 ( 5 14例 )的 90 .7% ,,占FBG正常例数的 15 .2 %。结论 :高血压、超重、年龄大于 4 0的患者即使FBG≤ 6 .0mmoI/L ,也应以餐后 2h血糖 ( 2hPG)

Objective:To evaluate the diagnostic effect of OGTT for DM and IGT when FBG is normal.Methods:To eliminate some patients with DM,acute diseases,surgery,acute or chronic hepatitis,pregnancy and the diseases that could affect metabolism of sugar by questionnaire,Other patients were tested OGTT.According to the level of 2h PG,they are classified into three groups:DM group,IGT group,and control group.Results:There are 91/292(31.2%)patients of DM and 466/514(90.7%) patients of IGT whose FBG≤6.0mmol/L and the rate was 2.96% and 15.2% respectively among 3071 normal FBG.Conclusion:The patients with hypertension,overweight and age more than 40 years old should test 2hPG to diagnose the DM and IGT even though FBG is normal.