白血病诱导分化治疗中的生态自然观

The Ecological Values in the Induction Therapy of Leukemia

诱导分化是一种治疗白血病的新方法 ,它通过促使分化不完全的肿瘤细胞分化成熟 ,使恶性转为良性。临床应用全反式维甲酸 (ATRA)和三氧化二砷 (As2 O3 )诱导急性早幼粒细胞性白血病取得了较高的完全缓解率 ,毒副作用也较低。诱导分化治疗策略突破了将杀灭肿瘤细胞作为治疗肿瘤的惟一方法的思维局限 ,谋求在与白血病细胞的和谐中获得人类的健康 ,是生态自然观应用于医疗实践的成功范例。

Differentiation induction is a new therapy for leukemia through influencing numerous signal transduction pathways and resulting in a vast range of cellular effects of promoting the differentiation of oncocytes. It has been proved that all-trans retinoic acid(ATRA) and arsenic trioxide(As 2O 3) have shown substantial efficacy in treating patients with acute promyelocytic leukemia-by inducing complete remissions while causing few adverse effects. This treatment is an important breakthrought in the mode of therapeutic thought. Trying to develop a harmonious relationship with malignant cells rather than killing them is likely to be much hopeful to keep healthy, and it is just the typical example of medical practice under the direction of ecological values.