系统性红斑狼疮合并妊娠19例分析

Systemic lupus erythematosus in pregnancy:clinical analysis of 19 cases.

目的 探讨系统性红斑狼疮 (SLE)患者合并妊娠后的病情恶化率以及妊高征发生率及妊娠期处理。方法 对1998～ 2 0 0 3年收治的 19例SLE合并妊娠的临床资料进行回顾性分析。结果 SLE合并妊娠后的病情恶化率及妊高征发生率分别为 5 2 6 %及 31 6 % ,与SLE病情活动和缓解有关。结论 SLE合并妊娠后病情容易加重 ,也易并发妊高征 ,应加强妊娠期监测和处理。

Objective To find out the rate of deterioration of systemic lupus erythematosus (SLE) during pregnancy,the incidence of co-existing pregnancy induced hypertension (PIH) and the ways of antepartum treatment.Methods A retrospective analysis of the clinical data was performed in 19 cases of SLE with pregnancy from 1998 to 2003.Results SLE with pregnancy had an acute deterioration rate of 52.6% and incidence of co-existing PIH of 52.6% and 31.6%,which were related to patients'condition and remissions.Conclusion When SLE happens in pregnancy,it is more likely to get worse and complicated with PIH.It is necessary to enhance the antepartum monitoring and treatment for these patients.